natalie23gill@gmail.com
Education
M.S. in Biology, Bioinformatics Focus
University of Oregon | June 2021 - expected December 2022
B.A. in Biological Sciences
Southern Methodist University | May 2020
Skills
| Programming | Analyses |
|---|---|
| R/Rstudio, Python, Bash, Git, Docker, GCP, BLAST, Slurm, Seurat | Demultiplexing, PCR Duplicate Removal, Genome Assembly, RNA-seq, scRNA-seq, WES |
Experience
Student Intern (Bioinformatics) | Earle A. Chiles Research Institute, Portland OR
April 2022 - Present
- Upgraded cloud-based and version controlled pipelines that analyze tumor and germline whole-exome sequencing (WES) data by standardizing legacy code and implementing new features
- Enabled an interdisciplinary team of researchers to assess potential response to immunotherapy by devising a pipeline that estimates tumor purity from WES of paired tumor and normal samples
- Scaled research methods in a cloud-based environment using Dockerfiles, Python, Bash and R.
Graduate Research Assistant | University of Oregon, Eugene OR
October 2021 - March 2022
- Analyzed scRNA-seq data from over 35,000 murine olfactory bulb cells to investigate the cell-type expression across samples from 10 developmental time points in collaboration - with the Yu lab at the Stowers Institute for Medical Research
- Developed pipelines utilizing R, Python, Bash, and multiple bioinformatics packages to clean the data and perform differential expression analysis on clusters generated using Seurat
- Developed and documented reproducible code using Git
Data Science Intern | Epic Sciences, San Diego CA
February 2020 - May 2021
- Wrote R analysis pipelines for circulating tumor cell (CTC) data from lung, breast, and prostate cancers
- Analyzed cell morphology, patient health, whole-genome single CTC sequencing, methylation, and RNA-seq results
- Prepared several analysis reports and presented results to large pharmaceutical clients, academic research groups, and cross-disciplinary teams within Epic
- Ensured the use of appropriate analytical methods and rigorous quality control measures through clear coding and documentation practices
- Coordinated with biopharma services personnel to complete precise manual data entry of over 10,000 CTCs for time-sensitive client needs spanning more than 10 clinical portfolios
Lab Assistant | Southern Methodist University, Dallas TX
August 2014 - May 2016
- Investigated the genetics of aging by performing lifespan assays on Drosophila melanogaster
- Prepared fly media, collected flies for new crosses, performed lifespan and behavioral assays, and prepared samples for GC/MS pheromone analysis
- Demonstrated decreasing desaturase levels negatively affects male lifespan while increasing female lifespan in flies and causes sex-specific variations in pheromone profiles
Publications and Presentations
Scher HI, Fernandez L, Cunningham K, Elphick N, Barnett E, Lee J, Gilbertson C, Carbone E, Bourdon D, Blankfard M, Wang E, Jones JT, Tubbs A, Anderson A, Schonhoft JD, Wenstrup R. 2021. Schlafen 11 (SLFN11), a putative predictive biomarker of platinum/PARPi response, is frequently detected on circulating tumor cells (CTCs) in advanced prostate cancer. JCO 39:e17039–e17039. doi:10.1200/JCO.2021.39.15_suppl.e17039
Joseph N, Elphick N, Mohammad S, Bauer J. 2018. Altered pheromone biosynthesis is associated with sex-specific changes in life span and behavior in Drosophila melanogaster. Mechanisms of Ageing and Development 176. doi:10.1016/j.mad.2018.10.002
Characterizing Interneuron Expression in the Developing Olfactory Bulb (January 2022).
Poster presented at the annual Genomics in Action held by the Knight Campus Graduate Internship Program to industry and academic partners. Link to poster and accompanying webpage.
Influence of Pheromones on the Longevity of the Fruit Fly (April 2016).
Presented to an audience of cross-disciplinary professionals and students at the Southern Methodist University Engaged Learning Undergraduate Research Symposium.